4.5 Article

Incidence of hip fractures in Greece during a 30-year period: 1977-2007

Journal

OSTEOPOROSIS INTERNATIONAL
Volume 24, Issue 5, Pages 1579-1585

Publisher

SPRINGER LONDON LTD
DOI: 10.1007/s00198-012-2154-z

Keywords

Fracture epidemiology; Greece; Hip fracture; Osteoporosis

Funding

  1. Amgen
  2. Pfizer
  3. Leo
  4. Genesis
  5. ELPEN
  6. Servier
  7. Merck
  8. Eli Lilly

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The incidence of hip fractures doubled in Greece from 1977 to 2007 among people aged 50 and over. A mild decrease was observed after 2002, although the future trend cannot be safely anticipated at the moment. Half of all hip fractures in 2007 were derived from the age group of 80 and over. The purpose of this study was to determine the incidence of hip fractures during a 30-year period in Greece among people aged 50 and over and to document possible alterations in secular trends. We studied hip fractures during 2007 and compared them with those of previous years starting from 1977 with an in-between 5-year interval (1977, 1982, 1987, 1992, 1997, 2002). Age- and sex-specific incidence was calculated, and secular trends were recorded. The relative risk of hip fracture in every age group was estimated according to the corresponding incidence of 1977. The adjusted incidence of hip fractures increased approximately 100 % throughout the study; it progressively increased from 1977 to 2002 and exhibited a mild significant decrease thereafter. The relative risk of hip fractures among subjects aged 60-69 in 2007 has declined compared with 1977 [0.85, 95 % confidence intervals (CI) 0.79-0.92, p < 0.0005]. Among people aged 70-79, an increased relative fracture risk (1.53, 95 % CI 1.45-1.61, p < 0.0005) was estimated in 2007 compared with 1977. People a parts per thousand yen80 years old were responsible for half of the hip fractures in 2007 but only for the 22.5 % of fractures in 1977. The relative fracture risk in people aged a parts per thousand yen80 was 2.81 times higher (95 % CI 2.64-2.98, p < 0.0005) in 2007 than in 1977. The incidence of hip fractures doubled during the last 30 years among people aged a parts per thousand yen50 years, although a mild decrease was observed in almost all age groups after 2002. The most affected group is 80 and over.

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