4.5 Article

Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

Clinical development success rates for investigational drugs

Michael Hay et al.

NATURE BIOTECHNOLOGY (2014)

Article Biochemistry & Molecular Biology

Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A

Robert Fledrich et al.

NATURE MEDICINE (2014)

Review Multidisciplinary Sciences

The Need for Randomization in Animal Trials: An Overview of Systematic Reviews

Jennifer A. Hirst et al.

PLOS ONE (2014)

Article Biochemistry & Molecular Biology

Reversible Folding of Human Peripheral Myelin Protein 22, a Tetraspan Membrane Protein

Jonathan P. Schlebach et al.

BIOCHEMISTRY (2013)

Review Neurosciences

Signals regulating myelination in peripheral nerves and the Schwann cell response to injury

Thomas D. Glenn et al.

CURRENT OPINION IN NEUROBIOLOGY (2013)

Review Clinical Neurology

Clinical implications of genetic advances in Charcot-Marie-Tooth disease

Alexander M. Rossor et al.

NATURE REVIEWS NEUROLOGY (2013)

Review Neurosciences

Molecular mechanisms regulating myelination in the peripheral nervous system

Jorge A. Pereira et al.

TRENDS IN NEUROSCIENCES (2012)

Review Clinical Neurology

Update on Charcot-Marie-Tooth Disease

Agnes Patzko et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2011)

Article Oncology

A new long term in vitro model of myelination

Noelle Callizot et al.

EXPERIMENTAL CELL RESEARCH (2011)

Article Neurosciences

Mouse Schwann Cells Need Both NRG1 and Cyclic AMP to Myelinate

Peter Arthur-Farraj et al.

Article Psychology, Biological

Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats

Pascal Tetreault et al.

PHYSIOLOGY & BEHAVIOR (2011)

Article Pharmacology & Pharmacy

Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research

Carol Kilkenny et al.

JOURNAL OF PHARMACOLOGY & PHARMACOTHERAPEUTICS (2010)

Review Biochemistry & Molecular Biology

Role of naturally occurring osmolytes in protein folding and stability

Raj Kumar

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)

Article Clinical Neurology

PMP22 expression in dermal nerve myelin from patients with CMT1A

Istvan Katona et al.

BRAIN (2009)

Review Neurosciences

Axon-glial signaling and the glial support of axon function

Klaus-Armin Nave et al.

ANNUAL REVIEW OF NEUROSCIENCE (2008)

Article Neurosciences

Pharmacological induction of the heat shock response improves myelination in a neuropathic model

Sunitha Rangaraju et al.

NEUROBIOLOGY OF DISEASE (2008)

Article Clinical Neurology

Neuropathy progression in Charcot-Marie-Tooth disease type 1A

M. E. Shy et al.

NEUROLOGY (2008)

Article Pharmacology & Pharmacy

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis

Thierry Bordet et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Pharmacology & Pharmacy

Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain

Bettina K. Beyreuther et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

Article Pharmacology & Pharmacy

An overview of drug combination analysis with isobolograms

Ronald J. Tallarida

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Pharmacology & Pharmacy

Isobolographic analysis for combinations of a full and partial agonist: Curved isoboles

Y Grabovsky et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Multidisciplinary Sciences

The neurotrophin receptor p75NTR as a positive modulator of myelination

JM Cosgaya et al.

SCIENCE (2002)

Article Genetics & Heredity

Molecular dissection of the Schwann cell specific promoter of the PMP22 gene

D Sabéran-Djoneidi et al.

Article Neurosciences

GABA(B) receptor protein and mRNA distribution in rat spinal cord and dorsal root ganglia

S Towers et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2000)