Journal
ORGANOMETALLICS
Volume 32, Issue 6, Pages 1563-1566Publisher
AMER CHEMICAL SOC
DOI: 10.1021/om301174s
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Funding
- World Class University (WCU) program [R33-2008-000-10003]
- Priority Research Centers program through the National Research Foundation of Korea (NRF) [2009-0093818]
- Ministry of Education, Science and Technology
- NIH [GM-57052]
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Two new supramolecular coordination complexes (SCCs) were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 mu M for MCF7 cells, as determined from MTS assays.
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