Journal
ORGANOMETALLICS
Volume 30, Issue 12, Pages 3242-3245Publisher
AMER CHEMICAL SOC
DOI: 10.1021/om200294x
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Funding
- World Class University program [R33-2008-000-10003]
- Priority Research Centers program [2009-0093818]
- Ministry of Education, Science and Technology
- National Research Foundation of Korea [R33-2011-000-10003-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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The synthesis of new 2+2 metallarectangles via coordination-driven self-assembly of octahedral Ru(II)-based acceptors and amide donors is described. To evaluate their in vitro cytotoxic properties, preliminary biological assays were carried out for various human cancer cell lines, and our results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin.
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