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Selective Platinum-Catalyzed C-F Bond Activation as a Route to Fluorinated Aryl Methyl Ethers

Journal

ORGANOMETALLICS
Volume 28, Issue 8, Pages 2356-2359

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/om900100f

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Funding

  1. University of British Columbia
  2. NSERC
  3. Merck Frosst
  4. Canada Foundation for Innovation
  5. British Columbia Knowledge Fund

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[(CH3)(2)Pt(mu-SMe2)](2)catalyzes the formation of aryl methyl ethers via selective C-F bond activation of polyfluoroarylimines. This reaction is functional group tolerant and proceeds in good to excellent yields. The optimization and preliminary substrate scope of this process are described.

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