Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 22, Issue 9, Pages 1063-1080Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.oprd.8b00232
Keywords
biocatalysis; transaminase; ketoreductase; nitrilase; imine reductase; dynamic reductive kinetic resolution; sulfur oxidation; hydroxylation
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The recent patent literature on biocatalysis is reviewed, with a focus on significant advances in enzymatic catalysis involving ketoreductases, transaminases, hydroxylases, sulfur oxidation, and nitrilase resolutions and a progress report on the emerging area of imine reductases highlighting collaborations between academia and pharmaceutical companies.
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