Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 14, Issue 4, Pages 912-917Publisher
AMER CHEMICAL SOC
DOI: 10.1021/op100139f
Keywords
-
Categories
Ask authors/readers for more resources
The triple reuptake inhibitor, GSK1360707, was synthesized via an efficient, scalable route, which features a vinyl triflate Suzuki coupling followed by a single-step, double alkylative cyclopropanation with a dihalomethane. Also, a mechanistic understanding of the Suzuki reaction (as it relates to the control of a polychlorinated biphenyl impurity) is discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available