Journal
ORGANIC LETTERS
Volume 16, Issue 3, Pages 756-759Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol403470d
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- CSIR, New Delhi [BSC0102, BSC0114]
- NIH National Center for Research Resources (NCRR)
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A new class of live cell permeant, nontoxic fluoranthene-based fluorescent probe (FLUN-550) having a high Stokes shift in aqueous medium has been discovered. It showed selective staining of lipid droplets (LDs, dynamic cytoplasmic organelles) at a low concentration without background noise in in vitro live cell imaging of 3T3-L1 preadipocytes, J774 macrophages, MCF7 breast cancer cells, and single-celled, parasitic protozoa Leishmania donovani promastigotes and in vivo nonparasitic soil nematode C. elegans.
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