4.8 Article

Efficient Synthesis of Aryl Boronates via Zinc-Catalyzed Cross-Coupling of Alkoxy Diboron Reagents with Aryl Halides at Room Temperature

Journal

ORGANIC LETTERS
Volume 16, Issue 17, Pages 4562-4565

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol502120q

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Funding

  1. Alexander von Humboldt Foundation (AvH)
  2. Deutsche Forschungsgemeinschaft (DFG)

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A zinc(II)/NHC system catalyzes the borylation of aryl halides with diboron (4) reagents in the presence of KOMe at it. This transformation can be applied to a broad range of substrates with high functional group compatibility. Radical scavenger experiments do not support a radical-mediated process.

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