Journal
ORGANIC LETTERS
Volume 16, Issue 11, Pages 2787-2789Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol500776j
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Funding
- ARC [LP0989338]
- Australian Research Council [LP0989338] Funding Source: Australian Research Council
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A new general methodology utilizing Minisci-type chemistry has been developed that cleanly and efficiently prepares alkyl- and (hydroxymethyl)pyrazines. The new methods eliminate toxic catalysts and halogenated solvents, providing a greatly improved route to these natural products which are prevalent in many natural systems as bacterial volatiles, plant volatiles, and insect pheromones.
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