Journal
ORGANIC LETTERS
Volume 16, Issue 4, Pages 1096-1099Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol403680c
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21202059]
- China Postdoctoral Science Foundation [2013M541287]
- Jilin Province Science & Technology Development Program [20100538, 20110436, 201215033]
Ask authors/readers for more resources
The first enantioselective synthesis of pyrrolyl-substituted triarylmethanes has been accomplished using a novel imidodiphosphoric acid catalyst, which is derived from two (R)BINOL frameworks with different 3,3'-substituents. This strategy was also expanded to the synthesis of bis(indolyl)-substituted triarylmethanes with high enantioselectivities, which could only be obtained with moderate ee values in previous reports. These two efficient Friedel-Crafts alkylation processes feature low catalyst loading, broad functional group compatibilities, and the potential to provide practical pathways for the synthesis of enantioenriched bioactive triarylmethanes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available