Journal
ORGANIC LETTERS
Volume 16, Issue 3, Pages 992-995Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol4037242
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Funding
- National Natural Science Foundation of China [21172200, 21102134]
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An efficient, mild, and generally applicable protocol for copper-mediated oxidative decarboxylative coupling of arylpropiolic acids with dialkyl H-phosphonates in water has been developed. Note that the reaction could proceed smoothly under air at relatively low temperature (60 degrees C), and the addition of isopropanol could successfully suppress the decomposition of dialkyl H-phosphonates in water.
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