Journal
ORGANIC LETTERS
Volume 16, Issue 9, Pages 2506-2509Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol500873s
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Funding
- Royal Society
- EPSRC
- GSK
- Pfizer
- EU
- European Research Council under the European Union [279850]
- European Research Council (ERC) [279850] Funding Source: European Research Council (ERC)
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Isothiourea HBTM-2.1 catalyzes the asymmetric Michael addition/lactonization of aryl- and alkenylacetic acids using alpha-keto-beta,gamma-unsaturated phosphonates as alpha,beta-unsaturated ester surrogates, giving access to a diverse range of stereodefined lactones or enantioenriched functionalized diesters upon ring-opening.
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