4.8 Article

Directed Additions of 2-Arylpyridines and Related Substrates to Cyclic Imines through Rhodium-Catalyzed C-H Functionalization

Journal

ORGANIC LETTERS
Volume 16, Issue 9, Pages 2538-2541

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol500918t

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Funding

  1. Alexander von Humboldt Foundation
  2. Gobierno Vasco
  3. China Scholarship Council

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Rhodium-catalyzed C-H functionalizations have been used for ortho-directed additions of 2-arylpyridines and (hetero)aryl-substituted pyrimidines, isoquinolines, and benzo[h]quinolones to cyclic imines. The resulting amino-functionalized products are formed in good to high yields.

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