Journal
ORGANIC LETTERS
Volume 16, Issue 20, Pages 5350-5353Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol502535z
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Funding
- Hundred Talent Program of Chinese Academy of Sciences (CAS)
- National Natural Science Foundation of China [21202175]
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A Bronsted acid accelerated Pd-catalyzed asymmetric allylic alkylation of azlactones with simple allylic alcohols under mild reaction conditions has been realized, which provides a direct and readily scalable approach for the synthesis of all-carbon quaternary allylic amino acid derivatives in excellent yields and good enantioselectivities.
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