Journal
ORGANIC LETTERS
Volume 16, Issue 11, Pages 3158-3161Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol501365j
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- NIH-NIGMS [R01GM101389-01]
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A complement to the classic three-component Mannich reaction, the redox-Mannich reaction, utilizes the same starting materials but incorporates an isomerization step that enables the facile preparation of ring-substituted beta-amino ketones. Reactions occur under relatively mild conditions and are facilitated by benzoic acid.
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