Journal
ORGANIC LETTERS
Volume 16, Issue 12, Pages 3292-3295Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol501293c
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Funding
- National Natural Science Foundation of China [21272183, 21002077]
- Fund of the Rising Stars of Shanxi Province [2012KJXX-26]
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A facile benzoyl peroxide (BPO) mediated ortho-hydroxylation and benzoylation of N-alkyl anilines for the synthesis of 2-benzamidophenols has been developed. The reaction tolerates a wide range of functional groups and is a good method for the straightforward synthesis of valuable 2-benzamidophenols in good yields under mild conditions.
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