4.8 Article

Ring-Opening 1,3-Dichlorination of Donor-Acceptor Cyclopropanes by Iodobenzene Dichloride

Journal

ORGANIC LETTERS
Volume 16, Issue 21, Pages 5804-5807

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol5029139

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Funding

  1. German Research Foundation (DFG, Emmy Noether and Heisenberg Fellowships)
  2. Fonds der Chemischen Industrie (Dozentenstipendium)

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Donor-acceptor cyclopropanes are reacted with iodobenzene dichloride to afford ring-opened products bearing chlorine atoms in the 1- and 3-positions, adjacent to the donor and acceptor groups. A variety of different donors (e.g., alkyl, aryl, N, and O) and acceptor moieties (e.g., ketones, diesters, and dinitriles) are used.

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