Journal
ORGANIC LETTERS
Volume 16, Issue 17, Pages 4598-4601Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol502173d
Keywords
-
Categories
Funding
- Institute for Basic Science (IBS)
- Ministry of Science, ICT & Future Planning, Republic of Korea [IBS-R010-D1-2014-A00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
The Rh(III)-catalyzed C-8 selective direct alkylation and alkynylation of quinoline N-oxides has been developed. The reactions proceeded highly efficiently at room temperature over a broad range of substrates with excellent regioselectivity and functional group tolerance. This development demonstrates the synthetic utility of the N-oxide directing group as a stepping stone for remote C H functionalization of quinolines.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available