Journal
ORGANIC LETTERS
Volume 16, Issue 11, Pages 2862-2864Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol5010033
Keywords
-
Categories
Funding
- JSPS KAKENHI [20002004, 25221301]
- Platform for Drug Discovery, Informatics, and Structural Life Science (MEXT)
- Sumitomo Foundation
- Tokyo Biochemical Research Foundation
Ask authors/readers for more resources
The first total synthesis of (-)-lepistine has been accomplished in 11 steps from (S)-glycidol. The synthesis features construction of the 10-membered ring via an intramolecular epoxide opening by nosylamide, regioselective dehydration to form an enol ether, and construction of the aminal moiety induced by cleavage of the nosyl groups.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
