4.8 Article

Practical Synthesis of Kainoids: A New Chemical Probe Precursor and a Fluorescent Probe

Journal

ORGANIC LETTERS
Volume 16, Issue 2, Pages 564-567

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol403434e

Keywords

-

Funding

  1. Uehara Memorial Foundation
  2. MEXT/JSPS KAKENHI [23390007, 22380114]
  3. Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan a [12045232, 24105530]
  4. Ministry of Education, Culture, Sports, Science and Technology
  5. Grants-in-Aid for Scientific Research [26860013, 24105530, 23390007, 24102525, 26102736, 22380114, 12045232, 25620137] Funding Source: KAKEN

Ask authors/readers for more resources

A practical total synthesis of kainoid MFPA (5) was achieved in only six steps, via a novel Ni-catalyst-mediated asymmetric conjugate addition reaction. Furthermore, a fluorescein-based fluorescent ionotropic glutamate receptor probe 28 was efficiently synthesized from a precursor derived from a synthetic intermediate of 5.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available