Journal
ORGANIC LETTERS
Volume 16, Issue 10, Pages 2630-2633Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol500792x
Keywords
-
Categories
Funding
- National Science Foundation from the Antarctic Organisms and Ecosystems program [ANT-1043749, ANT-0838776]
- National Institutes of Health from the National Institute of Allergy and Infectious Diseases [AI103673]
- Directorate For Geosciences
- Office of Polar Programs (OPP) [1043749] Funding Source: National Science Foundation
Ask authors/readers for more resources
The isolation and characterization of two new tricyclic sesquiterpenoids, shagenes A (1) and B (2) are presented. These compounds were isolated from an undescribed soft coral collected from the Scotia Arc in the Southern Ocean. One- and two-dimensional NMR spectroscopy and mass spectrometry provided the data necessary to characterize the compounds and their relative stereochemical configurations. Exploration of the bioactivity of shagenes A and B found 1 active against the visceral leishmaniasis causing parasite, Leishmania donovani, with no cytotoxicity against the mammalian host.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
