4.8 Article

Application of Cooperative Iron/Copper Catalysis to a Palladium-Free Borylation of Aryl Bromides with Pinacolborane

Journal

ORGANIC LETTERS
Volume 16, Issue 9, Pages 2366-2369

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol500675q

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Funding

  1. French Agence Nationale de la Recherche [EMMA 043-01]

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A new cooperative copper/iron catalysis for the borylation of various aryl bromides with pinacolborane, at -10 degrees C, is reported. Use of the toxic, precious metal Pd is avoided. The mechanism of the protodebromination side reaction is discussed.

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