Journal
ORGANIC LETTERS
Volume 15, Issue 12, Pages 3150-3153Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol4013712
Keywords
-
Categories
Funding
- Natural Science and Engineering Research Council of Canada (NSERC)
Ask authors/readers for more resources
A mild copper-catalyzed Chan-Lam-Evans type cross-coupling reaction for the regioselective and stereospecific preparation of (E)- or (Z)-enol esters is described. The method couples carboxylate salts or carboxylic acids with potassium alkenyltrifluoroborate salts In the presence of catalytic CuBr and DMAP with 4 angstrom molecular sieves under O-2 at 60 degrees C. Overall, this method demonstrates carboxylic acids as suitable reaction partners for nondecarboxylative copper-catalyzed cross-couplings to form C-O bonds in an Ullmann-like reaction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available