4.8 Article

Palladium-Catalyzed Direct α-Arylation of Methyl Sulfones with Aryl Bromides

Journal

ORGANIC LETTERS
Volume 15, Issue 7, Pages 1690-1693

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol400472v

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Funding

  1. National Science Foundation [CHE-0848460, 1152488]
  2. China Scholarship Council [2011635137]
  3. Direct For Mathematical & Physical Scien
  4. Division Of Chemistry [1152488] Funding Source: National Science Foundation

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A direct and efficient approach for palladium-catalyzed arylation of aryl and alkyl methyl sulfones with aryl bromides has been developed. The catalytic system affords arylated sulfones in good to excellent yields (73-90%).

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