Journal
ORGANIC LETTERS
Volume 15, Issue 5, Pages 1000-1003Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol3034466
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Funding
- National Major Scientific and Technological Special Project for Significant New Drugs Development of China [2011ZX09201-201-28]
- National Program on Key Basic Research Project of China (973 Program) [2012CB518606]
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Nardoaristolones A and B, two novel terpenoids derived from the aristolane-type sesquiterpenoid, were isolated from the underground parts of Nardostachys chinensis Batal. Nardoaristolone A is the first reported aristolane-chalcone derivative, while nardoaristolone B possesses a nor-aristolane sesquiterpenoid skeleton with an unusual 3/5/6 tricyclic ring system. Their structures were elucidated by spectroscopic measurements, and the absolute configurations were established by single-crystal X-ray diffraction experiments.
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