4.8 Article

Aspeverin, a New Alkaloid from an Algicolous Strain of Aspergillus versicolor

Journal

ORGANIC LETTERS
Volume 15, Issue 10, Pages 2327-2329

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol4009624

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Funding

  1. National Natural Science Foundations of China [41106136, 41106137]
  2. Foundations of Chinese Academy of Sciences for Key Topics in Innovation Engineering [KZCX2-YW-QN209]

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A novel carbamate- and cyano-containing alkaloid, aspeverin (1), was isolated from the culture of an algicolous Aspergillus versicolor strain (dl-29). The structure and absolute configuration were unambiguously identified by NMR, IR, ECD, and mass spectrometric methods as well as quantum chemical calculations. 1 exhibited potent bioactivities against some marine-derived organisms.

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