4.8 Article

Iron-Catalyzed One-Pot 2,3-Diarylquinazolinone Formation from 2-Nitrobenzamides and Alcohols

Journal

ORGANIC LETTERS
Volume 15, Issue 18, Pages 4900-4903

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol402350x

Keywords

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Funding

  1. National Natural Science Foundation of China [21172185, 21372187]
  2. Hunan Provincial Natural Science Foundation of China [11JJ1003, 12JJ7002]
  3. New Century Excellent Talents in University from Ministry of Education of China [NCET-11-0974]
  4. Research Fund for the Doctoral Program of Higher Education of China, Ministry of Education of China [20124301110005]

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A novel approach for the synthesis of 2,3-diarylquinazolinones using iron as catalyst is described. Various 2-nitro-N-arylbenzamides reacted with benzylic alcohols to selectively give the corresponding products in the absence of external oxidant or reductant.

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