Journal
ORGANIC LETTERS
Volume 15, Issue 9, Pages 2278-2281Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol400856g
Keywords
-
Categories
Funding
- Pfizer Global Research Development
- BP endowment
Ask authors/readers for more resources
A flow chemistry Meerwein-Ponndorf-Verley (MPV) reduction procedure using partially hydrated zirconium oxide via a machine-assisted approach is reported. The heterogeneous reductive system could be applied to a wide range of functionalized substrates, allowing clean and fast delivery of the alcohol products within a few minutes (6-75 min). In three examples the system was scaled to deliver 50 mmol of product.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available