4.8 Article

Asymmetric Oxidation Catalysis by a Porphyrin-Inspired Manganese Complex: Highly Enantioselective Sulfoxidation with a Wide Substrate Scope

Journal

ORGANIC LETTERS
Volume 15, Issue 22, Pages 5658-5661

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol402612x

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Funding

  1. National Basic Research Program of China [2009CB623505]

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The first genuinely promising porphyrin-inspired manganese-catalyzed asymmetric sulfoxidation method using hydrogen peroxide has been successfully developed, allowing for rapidly oxidizing (0.5-1.0 h) a wide variety of sulfides in high yields with excellent enantioselectivities (up to >99% ee).

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