Journal
ORGANIC LETTERS
Volume 16, Issue 1, Pages 270-273Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol403263c
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Funding
- National Natural Science Foundation [NSF21072081]
- National Basic Research Program of China (973 Program) [2010CB8-33203]
- 111 Project
- Program for Changjiang Scholars and innovative Research Team in University [IRT1138]
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A novel and highly practical reaction for the copper-catalyzed intermolecular cyanotrifluoromethylation of alkenes is presented here. This methodology provides a general and straightforward way to synthesize a variety of useful CF3-containing nitriles, which can be used for further preparation of pharmaceutically and agrochemically important compounds in synthetic organic chemistry.
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