4.8 Article

A Simple and Efficient Synthesis of 2,3-Diarylnaphthofurans Using Sequential Hydroarylation/Heck Oxyarylation

Journal

ORGANIC LETTERS
Volume 15, Issue 9, Pages 2190-2193

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol400738r

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Funding

  1. UGC, New Delhi [39-733/2010 (SR)]
  2. CSIR, New Delhi

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An efficient and simple strategy has been developed for the synthesis of 2,3-diarylnaphthofurans using sequential hydroarylation of naphthols and alkynes in the presence of In(OTf)(3) under microwave irradiation followed by one-pot Heck-oxyarylation of generated 1-substituted-alpha-hydroxy styrenes.

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