4.8 Article

Exploring the Unique Reactivity of Diazoesters: An Efficient Approach to Chiral β-Amino Acids

Journal

ORGANIC LETTERS
Volume 15, Issue 3, Pages 440-443

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol303011f

Keywords

-

Funding

  1. National Science Foundation [CHE-1145236]
  2. Stanford University
  3. Bayer Fellowship Program
  4. Division Of Chemistry
  5. Direct For Mathematical & Physical Scien [1145236] Funding Source: National Science Foundation

Ask authors/readers for more resources

The development of a highly stereospecific process for the C-O to C-N exchange with retention of configuration is described. This transformation enables access to optically enriched beta-amido-alpha-diazoesters. These products are transformed to beta-amino acids not readily accessible using known methods.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available