Journal
ORGANIC LETTERS
Volume 15, Issue 10, Pages 2334-2337Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol400437a
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Funding
- Ministry of Science and Technology [2011CB965300]
- National Natural Science Foundation of China [21142008]
- Tsinghua University
- Tsinghua University Initiative Scientific Research Program
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A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1,3-diols, and heterocycles through Ru-catalyzed C-H mono- and dihydroxylation of anilides has been developed with a new directing group strategy. The reaction demonstrates excellent reactivity, regioselectivity, good functional group tolerance, and high yields.
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