4.8 Article

Silver-Catalyzed Carboazidation of Arylacrylamides

Journal

ORGANIC LETTERS
Volume 15, Issue 16, Pages 4158-4161

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol402138y

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Funding

  1. NSFC [21072079, 21272100]
  2. Program for New Century Excellent Talents in University [NCET-11-0215]

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A novel and inexpensive method of nontoxic, silver-salt-catalyzed carboazidation of arylacrylamides to afford corresponding azide oxindoles is reported. This reaction system exhibits great functional group tolerance. All products form a crucial skeleton for the synthesis of various indole alkaloids.

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