4.8 Article

Removal of Ruthenium Using a Silica Gel Supported Reagent

Journal

ORGANIC LETTERS
Volume 15, Issue 21, Pages 5416-5419

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol402339e

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Funding

  1. NSF [CHE-1012839]
  2. Kapoor Graduate Fellowship
  3. Direct For Mathematical & Physical Scien
  4. Division Of Chemistry [1012839] Funding Source: National Science Foundation

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A solid-supported isocyanide ligand was developed to destroy active metathesis catalysts and to remove ruthenium byproducts from metathesis reactions. This method was able to significantly reduce the concentration of residual ruthenium from the organic products of several alkene and ene-yne metathesis reactions, under a variety of different conditions.

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