Journal
ORGANIC LETTERS
Volume 15, Issue 22, Pages 5750-5753Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol402796m
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- National Science Council of the Republic of China [NSC-102-2628-M-007-005]
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An efficient and mechanistically interesting method for the synthesis of highly substituted isoquinolines by a Rh(III)-catalyzed hydrazone directed ortho C H bond activation and annulation without an external oxidant is described. This reaction is accomplished via a C-C and C-N bond formation along with N-N bond cleavage.
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