Journal
ORGANIC LETTERS
Volume 15, Issue 12, Pages 3058-3061Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol401246u
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Funding
- Scripps Research Institute
- U.S. National Science Foundation [NSF CHE-1011898]
- Camille and Henry Dreyfus Foundation for a New Faculty Award
- A. P. Sloan Foundation
- China Scholarship Council for Oustanding Self-Financed Students Abroad Award
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1011898] Funding Source: National Science Foundation
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The Pd(II)-catalyzed intramolecular C-H amination of 2-pyridinesulfonyl-protected phenethylamine derivatives has been achieved using Phl(OAc)(2) as a bystanding oxidant, providing access to a variety of substituted indoline derivatives in good yields. The use of the 2-pyridlnesulfonyl protecting group allows for facile deprotection following C-H functionalization.
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