4.8 Article

MnO2 Promoted Sequential C-O and C-N Bond Formation via C-H Activation of Methylarenes: A New Approach to Amides

Journal

ORGANIC LETTERS
Volume 15, Issue 18, Pages 4908-4911

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol4023886

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Funding

  1. Department of Science and Technology, New Delhi [SR/S1/OC-78/2012]

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A novel and efficient approach for the synthesis of amides has been developed through manganese dioxide promoted nondirected C-H activation of methylarenes under mild reaction conditions employing N-chloroamines as effective coupling partners.

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