Journal
ORGANIC LETTERS
Volume 15, Issue 8, Pages 1838-1841Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol400451t
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Funding
- National Natural Science Foundation of China [20932002, 21172076, 21202046]
- National Basic Research Program of China (973 Program) [2011CB808600]
- Guangdong Natural Science Foundation [10351064101000000, S2012040007088]
- China Postdoctoral Science Foundation [2012T50673]
- Fundamental Research Funds for the Central Universities [2012ZP0003, 2012ZB0011]
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Palladium-catalyzed oxidative difunctionalization of enol ethers with 1,3-dicarbonyl compounds to construct trisubstituted furans in one step under mild conditions is described. The reaction is thought to proceed through a C-C bond formation along with a C-O bond closing the ring structure. Oxygen is the sole oxidant regenerating the Pd(II) catalyst.
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