Journal
ORGANIC LETTERS
Volume 15, Issue 13, Pages 3334-3337Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol4013734
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Funding
- Stellenbosch University
- Sasol
- Harry Crossley Foundation
- Commonwealth Scholarship
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The sense of asymmetric ortholithiation directed by a chiral oxazoline may be inverted simply by the choice of achiral ligand. Comparison of results with a number of ferrocenyl oxazoline derivatives suggests that lithiation takes place by coordination to the oxazoline nitrogen irrespective of the ligand used.
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