4.8 Article

Synthesis of Naphthalenes via Platinum-Catalyzed Hydroarylation of Aryl Enynes

Journal

ORGANIC LETTERS
Volume 14, Issue 22, Pages 5636-5639

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol302437v

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Funding

  1. NCRL [2012-0001245]
  2. BRL program [2009-0087013]
  3. National Research Foundation of Korea

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An efficient synthetic method of functionalized naphthalenes having hydrogen, alkyl, alkenyl, aryl, or heteroaryl groups on the 4-position and ethoxycarbonyl group on the 2-position was developed through selective Pt-catalyzed 6-endo intramolecular hydroarylation of ethyl (E)-2-ethynyl/alkynyl cinnamates.

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