Journal
ORGANIC LETTERS
Volume 14, Issue 10, Pages 2598-2601Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol3009057
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- EPB Center [R11-2008-052-01001]
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For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.
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