4.8 Article

Cross-Dehydrogenative Coupling between Enamino Esters and Ketones: Synthesis of Tetrasubstituted Pyrroles

Journal

ORGANIC LETTERS
Volume 14, Issue 6, Pages 1412-1415

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol300147t

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Funding

  1. Dalian Institute of Chemical Physics, Chinese Academy of Sciences

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Tetrasubstituted pyrroles have been synthesized via the cross-dehydrogenative coupling between enamino esters and acetone. Silver carbonate proved to be an effective oxidant, and no transition metal catalyst is necessary.

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