Journal
ORGANIC LETTERS
Volume 14, Issue 4, Pages 1066-1069Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol2031729
Keywords
-
Categories
Funding
- Japan Society for the Promotion of Science (JSPS)
- Daiichi Sankyo Co., Ltd.
- Kyoto University
- University of Tokyo
- Grants-in-Aid for Scientific Research [23685020, 22106524] Funding Source: KAKEN
Ask authors/readers for more resources
An efficient and high-yielding cross-coupling reaction of various primary, secondary, and tertiary alkyl chlorides with aryl Grignard reagents was achieved by using catalytic amounts of N-heterocyclic carbene ligands and iron salts. This reaction is a simple and efficient arylation method having applicability to a wide range of industrially abundant chloroalkanes, including polychloroalkanes, which are challenging substrates under conventional cross-coupling conditions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available