Journal
ORGANIC LETTERS
Volume 14, Issue 12, Pages 2996-2999Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol300988n
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Funding
- Spanish MINECO [SAF2007-61015, SAF2010-20822-C02, CSD2007-00006]
- ERDF
- Xunta de Galicia [INCITE09209084PR, GRC2010/12]
- Spanish MEC
- MINECO
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A practical protocol for the hydroalkynylation of enones using Pd catalysis is reported. The reaction proceeds efficiently with a variety of alkynes as well as with several cyclic and acyclic enones, providing synthetically relevant beta-alkynyl ketones in good to excellent yields.
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