Journal
ORGANIC LETTERS
Volume 14, Issue 9, Pages 2290-2292Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol3007106
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- Nanyang Technological University
- Singapore Ministry of Education
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A synthetic method of highly substituted quinolines has been developed from N-(2-alkynylaryl)enamine carboxylates under Cu-catalyzed aerobic conditions via intramolecular carbo-oxygenation of alkynes. This strategy was further applied for N-alkynylamidines for amino-oxygenation of alkynes, leading to imidazole and quinazoline derivatives.
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