4.8 Article

A Novel Amine Receptor Based on the Binol Scaffold Functions as a Highly Effective Chiral Shift Reagent for Carboxylic Acids

Journal

ORGANIC LETTERS
Volume 14, Issue 23, Pages 5813-5815

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol3027686

Keywords

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Funding

  1. National Natural Science Foundation of China [30900129]
  2. Natural Science Foundation of Zhejiang Province [Y2080331, LY12B02007, ZJST2009C34014, WZST H20080052, Y20100076]

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A smart receptor has been newly synthesized. NMR studies demonstrated that the receptor functions as a chiral shift reagent that is highly effective for determining the enantiomeric purity of a series of carboxylic acids, particularly those that have an a-oxygen atom.

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