4.8 Article

Total Syntheses of Chelidonine and Norchelidonine via an Enamide-Benzyne-[2+2] Cycloaddition Cascade

Journal

ORGANIC LETTERS
Volume 14, Issue 11, Pages 2742-2745

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol300967a

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Funding

  1. NIH [GM066055]

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Total syntheses of chelidonine and norchelidonine featuring an enamide-benzyne-[2 + 2] cycloaddition Initiated cascade is described. The cascade includes a pericyclic ring-opening and Intramolecular Diels-Alder reaction.

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