4.8 Article

Ru(II)-Catalyzed C-H Bond Activation for the Synthesis of Substituted Isoquinolinium Salts from Benzaldehydes, Amines, and Alkynes

Journal

ORGANIC LETTERS
Volume 14, Issue 13, Pages 3478-3481

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol301445r

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Funding

  1. National Science Council of the Republic of China [NSC-100-2119-M-007-002]

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An efficient method for the synthesis of substituted isoquinolinium salts from benzaldehydes, amines, and alkynes via ruthenium-catalyzed C-H bond activation and annulation in one pot is described.

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